Special Issue: Advanced techniques of MALDI-TOF MS in ionization, instrumentation and applications

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MALDI-TOF MS in Prenatal Genomics.

Prenatal diagnosis aims either to provide the reassurance to the couples at risk of having an affected child by timely appropriate therapy or to give the parents a chance to decide the fate of the unborn babies with health problems. Invasive prenatal diagnosis (IPD) is accurate, however, carrying a risk of miscarriage. Non-invasive prenatal diagnosis (NIPD) has been developed based on the exist...

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Identification of Candida species isolated from vulvovaginitis in Mashhad, Iran by Use of MALDI-TOF MS

Background and Purpose Vulvovaginal candidiasis (VVC) is a common problem in women. The purpose of this study was to identify of Candida species isolated from vulvovaginitis woman suffering vulvovaginitis refered to Ghaem Hospital, Mashhad, Iran, by use of MALDI-TOF mass spectrometry.  Materials and Methods The 65 clinical samples isolated from Vulvovaginitis women were collected in...

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Use of Soft and Hard Ms Ionization Techniques for Unknown Compounds Elucidation by Gc-tof Ms

Investigation of trace level non-target compounds by GC-MS often is a challenging task that requires powerful software tools to detect the unknown components, to obtain the deconvoluted mass spectra, and to interpret the data if no acceptable library match is obtained. In this paper, the complementary use of EI and CI is investigated in combination with GCTOF MS for the elucidation of organic n...

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Dossier MALDI - TOF ■ Oligonucleotide analysis by MALDI - MS

Matrix-assisted laser desorption (MALDI) time-offlight (TOF) mass spectrometry (MS) has been successfully used for oligonucleotide sequence confirmation by mass analysis of fragments generated by concentration-dependent exonuclease digestion. This approach is particularly well-suited to the analysis of synthetic DNA due to the relatively short length of the DNA strands. Additionally, an importa...

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Matrix-assisted laser desorption ionization time-of-flight mass-spectroscopy (MALDI-TOF MS)

10 # Corresponding Author: Mailing address: Karen C. Carroll, Johns Hopkins Hospital 11 Microbiology Laboratory, Meyer B1-193, 600 N. Wolfe St., Baltimore MD 21287; 410-95512 5077; FAX 410-614-8087; [email protected] 13 Copyright © 2012, American Society for Microbiology. All Rights Reserved. J. Clin. Microbiol. doi:10.1128/JCM.01405-12 JCM Accepts, published online ahead of print on 1 August 2012

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ژورنال

عنوان ژورنال: Mass Spectrometry

سال: 2012

ISSN: 2187-137X

DOI: 10.5702/massspectrometry.k0002